Clinical and Functional Evolution in Subjects with Parkinson’s Disease during SARS-CoV-2 Pandemic

The COVID-19 pandemic has been a stress test for the population, especially people with chronic disorders such as Parkinson’s disease (PD). In addition to public health restrictions that contrast PD management recommendations, there were deep changes in care delivery. This retrospective study evaluates impact of on clinical and functional evolution cohort 221 patients consecutively referred Movement Disorders Center between 2018 2021. We analyzed trend motor non-motor symptoms status across years based Unified Disease Rating Scale (UPDRS) Non-Motor Symptom (NMSS). also compared number emerging complications, neurologic visits, rehabilitation sessions per subject year. 2020, all primary endpoint measures worsened 2019, without age, duration, or greater impairment explaining this outcome. Concurrently, percentage receiving visits reduced by 53% 58%, respectively. subgroup analysis 167 subjects revealed those who received at least one cycle 2020 maintained their independence level. These findings lead emphasizing importance regular monitoring delivery neurological disorders.